In vivo Pharmacology

  • Development of animal models capable of representing the sphere of psychiatric disorders such as depression, anxiety and schizophrenia. 
  • Identifying target on which to develop new strategies for therapeutic intervention.

 

Animal models available: 

  • Fear conditioning and non-conditioning
  • Paradigms of anxiety / conflict
  • Stress sensitization
  • Animal models of psychosis
  • Catalepsy and dyskinesia 
  • Models for the assessment of cognitive performance and memory and learning 
  • Animal models of depression
  • Mouse model of glaucoma

 

All studies are carried out with the help of automated equipment for the quantification of behavioural responses.
In vivo method for the study of many biological parameters both in the CNS and peripheral nervous system:

  • Brain Microdialysis: determination and quantification of the levels of neurotransmitters and their metabolites
  • Pain: test of analgesia in acute and chronic (neuropathic pain, inflammatory pain)
  • Eating disorders: animal models of obesity and measurement of feeding behaviour in acute and chronic
  • Inflammation: models of intestinal and genital-urinary inflammation

Credits: Imedia di Giulio Lai e C. s.a.s. - Realizzazione siti internet, sviluppo software e multimedia - Cagliari