Cell Biology

In vitro study of the mechanisms of drug action and analysis of interactions between cells in physiological and pathological conditions, in standard cell lines or primary cultures derived from brain tissue. 

  • Gene expression of various receptors
  • Alterations of neural development
  • Determination of cito-toxicity due to acute and chronic drug treatments
  • Identification of the intracellular mechanism of action of drugs
  • Extraction and purification of proteins and / or nucleic acids
  • Studies of apoptosis and toxicity assays by using immunocytochemistry and ATP-lite
  • Simulation of in vitro blood-brain barrier
  • Metabolic studies in vitro

 

Main equipment used: 

  • System for Western Blot
  • Fluorimeter
  • The highly standardized protocols allow us to perform rapid screening of new synthetic compounds.

Credits: Imedia di Giulio Lai e C. s.a.s. - Realizzazione siti internet, sviluppo software e multimedia - Cagliari